Search Results - diagnostics

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Quantitative rapid diagnostic platform using porous silicon on paper

Summary While medical diagnostics today typically tradeoff between speed and sensitivity, Vanderbilt researchers have developed a diagnostic platform that is both rapid and quantitative by coupling lateral flow paper-based tests with color changing porous silicon membranes. This platform can be adapted to detect a wide range of biological and chemical...

Published: 10/31/2024 | Inventor(s):

Keywords(s):

Category(s): Diagnostics

One-Step Hydrosilylation for Click Chemistry Compatible Surfaces

Summary Vanderbilt inventors have developed a one-step hydrosilylation synthesis of azide surfaces for the preparation of click chemistry compatible substrates. In this process, an organic azide is formed in a single step on a hydrogen-terminated silicon support, yielding a surface that is ready to undergo click reactions as desired. Simple, efficient,...

Published: 7/9/2024 | Inventor(s):

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Category(s): Diagnostics, Thin Films & Nanomaterials

PIQASO: A rigid phantom for comprehensive end-to-end evaluation of online adaptive radiotherapy systems

Summary There is currently no radiotherapy phantom capable of quantitatively assessing all components of an online adaptive radiotherapy (online ART) system in a comprehensive end-to-end test. Represented here is a novel, rigid phantom that can simultaneously evaluate an online ART system’s image acquisition, deformable image registration, contour...

Published: 8/10/2021 | Inventor(s):

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Category(s): Diagnostics, Medical Devices, Medical Imaging

Bioresorbable RF Coils for Post-Surgical Monitoring by MRI

Summary Vanderbilt researchers have developed bioresorbable RF coils to improve the signal-to-noise ratio (SNR) for use in post-surgical monitoring. Addressed Need Current MRI techniques have difficulty imaging certain biomarkers and characteristics internal to the body due to an insufficient signal-to-noise ratio (SNR). One approach to mitigate this...

Published: 8/2/2021 | Inventor(s):

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Category(s): Diagnostics, Medical Imaging

Advanced Ultrasound Imaging for Kidney Stone Detection

SummaryThe standard for kidney stone detection is through the use of computed tomography (CT). However, CT is expensive and delivers harmful ionizing radiation into the body. Ultrasound would be the ideal way to detect kidney stones except that it performs poorly in detecting and accurately sizing stones. Vanderbilt researchers inventors have developed...

Published: 11/6/2018 | Inventor(s):

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Category(s): Diagnostics, Medical Imaging

Speculum-Free Diagnostic Probe for Optical Assessment of the Cervix

SummaryA new approach for obtaining less invasive optical measurements of the cervix has been developed that does not require the use of a speculum exam. This technology can visualize the cervix in vivo to find unique biomarkers that indicate various conditions such as preterm labor, cancer, human papillomavirus (HPV), and dysplasia.Addressed NeedOptical...

Published: 7/9/2024 | Inventor(s):

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Category(s): Medical Imaging, Medical Devices, Diagnostics

Adaptive PCR: A PCR control system to overcome challenging conditions

Applications By directly monitoring the hybridization of fluorescent-labeled L-DNA mimics of the template DNA strands and primers, it is possible to improve the efficiency of PCR in challenging conditions. This approach eliminates some of the sample preparation and trial and error that would otherwise be required for difficult sample types such as urine...

Published: 4/11/2023 | Inventor(s):

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Category(s): Diagnostics, Medical Devices

A Novel Organs-On-Chip Platform

Summary Vanderbilt researchers have created a new multi-organs-on-chip platform that comprises Perfusion Control systems, MicroFormulators, and MicroClinical Analyzers connected via fluidic networks. The real-time combination of multiple different solutions to create customized perfusion media and the analysis of the effluents from each well are both...

Published: 7/9/2024 | Inventor(s):

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Category(s): Medical Devices, Microfluidics, Research Tools, Diagnostics

Non-Invasive Bacterial Identification for Acute Otitis Media using Raman Spectroscopy

Summary Vanderbilt researchers have developed an optical-based method for real-time characterization of middle ear fluid in order to diagnose acute otitis media, also knows as a middle ear infection. The present technique allows for quick detection and identification of bacteria and can also be applied to other biological fluids in vivo.Addressed NeedOtitis...

Published: 7/9/2024 | Inventor(s):

Keywords(s): Infectious Disease

Category(s): Diagnostics, Medical Imaging, Medical Devices

Low-cost, Normally Closed Microfluidic Valve

SummaryVanderbilt researchers have developed a normally closed valve that is able to provide selective movement of small fluid quantities in a microfluidic device. The present microfluidic valve can be actuated using a simple rotating drivehead and mechanical support, greatly simplifying the valve design.Addressed NeedMicrofluidics is a rapidly growing...

Published: 7/9/2024 | Inventor(s):

Keywords(s):

Category(s): Diagnostics, Microfluidics

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