Search Results - cardiovascular

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pECHO: Easy to Use Smartphone App for Assisting in Transesophageal Echocardiography Exam

Summary Transesophageal echocardiography (TEE) is a test that uses high-frequency sound waves to create images of the heart. It provides more detail that a standard echocardiogram. Vanderbilt researchers have created a software that creates an easy to follow, step-by-step procedure for a transesophageal echocardiography exam.Addressed NeedThe pECHO...

Published: 5/29/2019 | Inventor(s):

Keywords(s): Cardiovascular

Category(s): Computer Science & Communications, Health Care IT, Medical Imaging

Long-Lasting and Self-Sustaining Cell Therapy System

SummaryCurrent T-cell therapies rely on the successful transplant and survival of infused, therapeutic cells in a patient. The efficacy of a cell therapy is limited by the extent of cell survival after adoptive cell transfer (ACT) and by the stability of the engraftment. Poor engraftment of transplanted cells results in loss of therapeutic efficacy,...

Published: 2/7/2023 | Inventor(s):

Keywords(s): Cardiovascular, Inflammatory/Immune/Wound Repair, Oncology

Category(s): Therapeutics, Vaccines

Automated Inflatable Binder to Counter the Effects of Orthostatic Hypotension

Summary Orthostatic hypotension (OH) is a chronic, debilitating illness that can cause instability and dizziness upon standing, leading to increased risk of injury from a fall. OH affects millions of people every year, especially the elderly, hindering movement and physical activity and, in the worst cases, causing syncope or death. OH and impaired...

Published: 1/23/2018 | Inventor(s):

Keywords(s): Cardiovascular

Category(s): Medical Devices

Novel Anti-Platelet Therapy for the Treatment of Thrombosis and Cerebrovascular Injury by Targeting PAR-4

Technology DescriptionCardiovascular disease remains one of the leading causes of death in developed countries. Thromboembolism is a potentially serious cardiovascular condition, in which a blood clot forms (thrombosis) in an injured blood vessel in combination with a risk for embolism. Protease-activated receptors 1 and 4 (PAR1, PAR4) are found on...

Published: 1/23/2024 | Inventor(s): Heidi Hamm, Shaun Stauffer, Craig Lindsley, Summer Young

Keywords(s): Cardiovascular

Category(s): Therapeutics

Slc5a7 (choline transporter, CHT) BAC Transgenic Mouse

A Bacterial Artificial Chromosome (BAC) containing the mouse Slc5a7 gene was used to make transgenic mice. Mice show elevated choline transporter and acetylcholine levels and increased treadmill endurance. These mice permit the study of elevated presynaptic choline transporter protein in vivo, expressed solely in cholinergic neurons due to the BAC...

Published: 4/18/2016 | Inventor(s):

Keywords(s): Analgesic, Cardiovascular, Inflammatory/Immune, Metabolic Disorders/ Diabetes, Neuroscience/Neurology

Category(s): Research Tools

Scn1a Knockout Mouse Genetic Model of Epilepsy

This is a unique genetically modified strain of mice that models Dravet syndrome, a severe infant-onset epileptic encephalopathy. They are maintained on apure 129S6/SvEvTac genetic background to facilitate genetic studies.References:Miller AR, Hawkins NA, McCollom CE, Kearney JA (2014) Mapping genetic modifiers of survival in a mouse modelof Dravet...

Published: 5/31/2023 | Inventor(s):

Keywords(s): Cardiovascular, Neuroscience/Neurology

Category(s): Research Tools

Luciferase Reporter System for Viral Detection in Vitro and in Vivo

This research targets Respiratory Syncytial Virus.

Published: 4/11/2023 | Inventor(s): R. Stokes Peebles, Martin Moore, Melanie Aston, Michael Chi, Monica Deterding, Matthew Huckabee

Keywords(s): Cardiovascular, Infectious Disease

Category(s): Research Tools

Endothieal Nitric Oxide Synthase Null Mice (db/db background)

This research targets eNOS.

Published: 5/31/2023 | Inventor(s): Raymond Harris

Keywords(s): Cardiovascular