Search Results - Jack

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Fused in Sarcoma (FUS) Nuclear Translocation Inhibitors for Preventing Fibrosis

Summary Vanderbilt researchers Manuel Chiusa, Ambra Pozzi, Jack Hawiger, and Jozef Zienkiewicz have developed a new therapeutic approach to combat excess collagen production associated with fibrotic diseases. This approach aims to further understand and downregulate the expression of the tyrosine phosphorylated ribonucleoprotein Fused in Sarcoma (FUS)...

Published: 6/17/2025 | Updated: 6/28/2019 | Inventor(s):

Keywords(s):

Category(s): Therapeutics

Purified Bovine cAMP and cGMP Dependant Protein Kinases

This research targets PKA, PKG.

Published: 5/31/2023 | Updated: 3/20/2013 | Inventor(s): Jackie Corbin

Keywords(s): Cardiovascular

Category(s): Research Tools

Cell-Permeable Socs Proteins That Inhibit Cytokine-Induced Signaling

SummaryScientists at Vanderbilt have developed a unique intracellular protein therapy as a facile alternative to gene therapy. By engineering cell-penetrating recombinant SOCS proteins (CP-SOCSs) designed to inhibit cytokine signaling inside the cell they prevented or treated acute inflammation in the liver and other major organs in preclinical models....

Published: 2/7/2023 | Updated: 1/28/2013 | Inventor(s): Jack Hawiger

Keywords(s):

Category(s): Therapeutics

Method for the Automatic Segmentation of the Facial Nerve and the Chorda Tympani in CT Images

This is a high resolution imaging device that can detect the fundamental functional units of cortical organization. Currently, with existing technology, we are able to monitor the activity of these units in the awake, head-fixed animal using large standard sized cameras mounted on heavy camera arms. However, we need a capability to conduct such monitoring...

Published: 3/13/2012 | Updated: 3/23/2009 | Inventor(s): Benoit Dawant

Keywords(s):

Category(s): Medical Devices / Imaging, Medical