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Cell-Permeable Socs Proteins That Inhibit Cytokine-Induced Signaling

SummaryScientists at Vanderbilt have developed a unique intracellular protein therapy as a facile alternative to gene therapy. By engineering cell-penetrating recombinant SOCS proteins (CP-SOCSs) designed to inhibit cytokine signaling inside the cell they prevented or treated acute inflammation in the liver and other major organs in preclinical models....

Published: 2/7/2023 | Updated: 1/28/2013 | Inventor(s): Jack Hawiger

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Category(s): Therapeutics