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Prevention of Cytokine Induced Apoptosis In Intestinal Epithelial Cells By A Probiotic Bacterium

SummaryVanderbilt researchers have discovered a novel peptide, p40, derived from one of the best-studied probiotic bacteria in clinical trials, Lactobacillus rhamnosus GG (LGG). This peptide transactivates EGF receptor signaling in intestinal epithelial cells. As a consequence, p40 is capable of maintaining intestinal homeostasis by decreasing epithelial...

Published: 5/31/2023 | Inventor(s): Brent Polk

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Category(s): Therapeutics